Florence County
* American Red Cross - Pee Dee Chapter
* Boys & Girls Clubs of the Pee Dee Area
* DUBS ETC - recycle and refurbish computer equipment and provide these to the disabled and disadvantaged
* Family Service Center of South Carolina
* Fatherhood & Families Engagement Program - Fatherhood Initiative
* Florence County Citizens In Action - government watchdog group
* Florence County Disabilities and Special Needs Board
* House of Hope of the Pee Dee - helps the homeless
* Johnsonville Lions Club
* Lighthouse Ministries - provides financial assistance to families and individuals with limited resources
* Manna House - soup kitchen
* Mercy Medicine Clinic - free clinic
* Parentwise - offers information to parents concerning their child's education
* Pee Dee Coalition Against Domestic and Sexual Violence
* South Carolina Volunteer Guardian ad Litem Program - Florence County - voices for children in foster care
* United Way of Florence County
Horry County
* Aynor Volunteer Rescue Squad
* Boys & Girls Club of the Grand Strand
* Caring in our Lifetime - providing financial assistance with medical expenses of breast cancer
* Coastal South Carolina Chapter of the American Red Cross
* Goodwill Industries of Lower South Carolina
* GrAce Ministries - nonprofit geriatric care
* Habitat for Humanity of Horry County
* Helping Hand of Myrtle Beach - providing assistance for those in need
* Kiwanis Club of Conway
* Meals on Wheels of Horry County
* MOMS Club of Conway
* Myrtle Beach Civitan Club
* Newcomers Club of the Grand Strand
* North Myrtle Beach Rescue - volunteer emergency medical team
* Promise Land Ministries - Galivant's Ferry - helping troubled youth, needy adults
* Sea Haven - North Myrtle Beach - helping homeless youth in Horry County
* SharedCare - helping those in need find health care
* SOS Health Care - S.O.S. - United Way Agency
* South Carolina Volunteer Guardian ad Litem Program - Horry County - voices for children in foster care
* Step Up! - Myrtle Beach volunteer network matching people who want to volunteer with organizations.
* Street Reach Ministires - helping the homeless
* United Way of Horry County
* Waccamaw Community Foundation - Myrtle Beach
* Waccamaw Youth Center - Conway - residential center
Marion County
*American Red Cross - Pee Dee Chapter
*Fatherhood & Families Engagement Program - Fatherhood Initiative
*Marion Lions Club
*Pee Dee Coalition Against Domestic and Sexual Violence
*South Carolina Volunteer Guardian ad Litem Program - Marion County - voices for children in foster care
Williamsburg County
*Caring and Sharing - food bank and financial assistance for the needy
*Coastal South Carolina Chapter of the American Red Cross
*Georgetown County United Way - also serves Williamsburg County
*Pee Dee Coalition Against Domestic and Sexual Violence
*South Carolina Volunteer Guardian ad Litem Program - Williamsburg County - voices for children in foster care